HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: PRP16 (Q92620)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.4.13) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38)
Gene: DHX38

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30585729
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane and 1 others more... GO:0016887 - ATP hydrolysis activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 1227
+	Hs
		523750 XRCC6_HUMAN (1-609): 0: 666: 100.00		DHX8_HUMAN (209-1182): 0: 818: 40.40
+	Hs
		224755 XRCC6_HUMAN (1-609): 0: 666: 100.00		DHX16_HUMAN (278-1168): 0: 743: 41.01
+	Hs
		523695 XRCC6_HUMAN (1-609): 0: 666: 100.00		DHX9_HUMAN (264-1173): 0: 723: 21.98
+	Hs
		524892 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		DHX9_HUMAN (264-1173): 0: 723: 21.98