HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 127
+	Hs
		523794 XRCC6_HUMAN (1-609): 0: 666: 100.00		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		523545 XRCC6_HUMAN (1-609): 0: 666: 100.00		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		523652 XRCC6_HUMAN (1-609): 0: 666: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		524943 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		524806 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		H2B1B_HUMAN (1-127): 6.87e-54: 166: 85.83
+	Hs
		524869 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Sc
		356005 KU80_YEAST (36-591): 1.04e-109: 344: 15.33		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36
+	Sc
		355839 KU70_YEAST (19-518): 5.76e-105: 331: 18.82		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36