HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: TONSL (Q96HA7)
Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)
Gene: TONSL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21113133
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 1378
+	Hs
		525018 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		310032 XRCC6_HUMAN (1-609): 0: 666: 100.00		TNKS1_HUMAN (328-846): 2.79e-46: 184: 12.75
+	Hs
		523964 XRCC6_HUMAN (1-609): 0: 666: 100.00		BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18
+	Hs
		174588 XRCC6_HUMAN (1-609): 0: 666: 100.00		OGT1_HUMAN (2-241): 3.04e-15: 83.3: 15.29
+	Hs
		525035 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18