HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25817432, 27248496, 31353912
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 626
+	Hs
		523904 XRCC6_HUMAN (1-609): 0: 666: 100.00		DDB2_HUMAN (201-625): 1.38e-70: 236: 21.51
+	Hs
		525062 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Hs
		523645 XRCC6_HUMAN (1-609): 0: 666: 100.00		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		523698 XRCC6_HUMAN (1-609): 0: 666: 100.00		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		525001 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		DDB2_HUMAN (201-625): 1.38e-70: 236: 21.51
+	Sc
		979564 KU80_YEAST (36-591): 1.04e-109: 344: 15.33		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Sc
		698532 KU70_YEAST (19-518): 5.76e-105: 331: 18.82		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Hs
		524866 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23