Interactor 1: LYL1 (P12980)
Protein lyl-1 (Class A basic helix-loop-helix protein 18) (bHLHa18) (Lymphoblastic leukemia-derived sequence 1)
Gene: LYL1

Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.573

The method score is based on:

Property Details
Experiments 10023675
Identification Methods pull down, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 280
Hs

1 968
+ Hs
+ Hs
+ Dm
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+ Hs
+ Hs
+ Dm
+ Dm
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+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024