HitPredict

Interactor 1: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Interactor 2: SMO (P91682)
Protein smoothened (dSMO) (SMOH) (Smooth)
Gene: SMO

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21730325
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007346 - regulation of mitotic cell cycle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 302 Dm			1 1036
+	Dm
		819205 PP11_DROME (1-301): 0: 547: 96.68		SMO_DROME (1-1036): 0: 1567: 100.00
+	Dm
		954738 PP13_DROME (1-302): 0: 539: 93.71		SMO_DROME (1-1036): 0: 1567: 100.00
+	Dm
		819250 PP1B_DROME (1-302): 0: 530: 85.48		SMO_DROME (1-1036): 0: 1567: 100.00
+	Hs
		737920 PP1G_HUMAN (3-301): 0: 549: 93.31		SFRP1_HUMAN (91-250): 3.54e-41: 156: 18.41
+	Hs
		906019 PP1A_HUMAN (2-301): 0: 549: 92.67		SFRP1_HUMAN (91-250): 3.54e-41: 156: 18.41
+	Hs
		906532 PP1B_HUMAN (1-302): 0: 538: 87.79		SFRP1_HUMAN (91-250): 3.54e-41: 156: 18.41
+	Hs
		737974 PP1G_HUMAN (3-301): 0: 549: 93.31		SFRP2_HUMAN (86-204): 4.57e-36: 140: 21.31
+	Hs
		906078 PP1A_HUMAN (2-301): 0: 549: 92.67		SFRP2_HUMAN (86-204): 4.57e-36: 140: 21.31
+	Hs
		737855 PP1G_HUMAN (3-301): 0: 549: 93.31		SFRP5_HUMAN (91-199): 4.19e-35: 138: 17.86
+	Hs
		905956 PP1A_HUMAN (2-301): 0: 549: 92.67		SFRP5_HUMAN (91-199): 4.19e-35: 138: 17.86
+	Hs
		906559 PP1B_HUMAN (1-302): 0: 538: 87.79		SFRP2_HUMAN (86-204): 4.57e-36: 140: 21.31
+	Hs
		906488 PP1B_HUMAN (1-302): 0: 538: 87.79		SFRP5_HUMAN (91-199): 4.19e-35: 138: 17.86