HitPredict

Interactor 1: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Interactor 2: Q4V424 (Q4V424)
IP09433p (IP09533p)
Gene: DmelCG12620

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.693

Property	Details
Experiments	14605208, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 302 Dm			1 287
+	Dm
		819260 PP1B_DROME (1-302): 0: 530: 85.48		Q4V424_DROME (1-287): 6.35e-115: 334: 100.00
+	Hs
		737628 PP1G_HUMAN (3-301): 0: 549: 93.31		IPP2_HUMAN (1-156): 7.12e-43: 147: 19.88
+	Hs
		782714 PP1A_HUMAN (2-301): 0: 549: 92.67		IPP2_HUMAN (1-156): 7.12e-43: 147: 19.88
+	Mm
		906370 PP1A_MOUSE (2-301): 0: 550: 92.33		IPP2_MOUSE (1-156): 2.26e-42: 146: 21.05
+	Hs
		737869 PP1G_HUMAN (3-301): 0: 549: 93.31		IPP2B_HUMAN (1-156): 1.43e-40: 141: 19.88
+	Hs
		905971 PP1A_HUMAN (2-301): 0: 549: 92.67		IPP2B_HUMAN (1-156): 1.43e-40: 141: 19.88
+	Hs
		782715 PP1B_HUMAN (1-302): 0: 538: 87.79		IPP2_HUMAN (1-156): 7.12e-43: 147: 19.88
+	Hs
		164067 PP1G_HUMAN (3-301): 0: 549: 93.31		IPP2C_HUMAN (3-141): 2.86e-36: 130: 19.46
+	Hs
		164068 PP1A_HUMAN (2-301): 0: 549: 92.67		IPP2C_HUMAN (3-141): 2.86e-36: 130: 19.46
+	Hs
		906500 PP1B_HUMAN (1-302): 0: 538: 87.79		IPP2B_HUMAN (1-156): 1.43e-40: 141: 19.88
+	Dm
		65574 PP12_DROME (1-302): 0: 547: 100.00		A8JNP7_DROME (3-162): 2.4e-34: 128: 24.41
+	Dm
		65575 PP11_DROME (1-301): 0: 547: 96.68		A8JNP7_DROME (3-162): 2.4e-34: 128: 24.41
+	Hs
		164069 PP1B_HUMAN (1-302): 0: 538: 87.79		IPP2C_HUMAN (3-141): 2.86e-36: 130: 19.46
+	Dm
		65577 PP13_DROME (1-302): 0: 539: 93.71		A8JNP7_DROME (3-162): 2.4e-34: 128: 24.41
+	Dm
		524639 PP12_DROME (1-302): 0: 547: 100.00		Q9V3C7_DROME (3-162): 5.31e-29: 111: 24.41
+	Dm
		65576 PP1B_DROME (1-302): 0: 530: 85.48		A8JNP7_DROME (3-162): 2.4e-34: 128: 24.41
+	Dm
		819222 PP11_DROME (1-301): 0: 547: 96.68		Q9V3C7_DROME (3-162): 5.31e-29: 111: 24.41
+	Dm
		984191 PP13_DROME (1-302): 0: 539: 93.71		Q9V3C7_DROME (3-162): 5.31e-29: 111: 24.41
+	Ce
		821925 GLC7B_CAEEL (3-301): 0: 550: 90.97		Q9N537_CAEEL (5-106): 1.15e-20: 88.8: 16.54
+	Ce
		1099877 GLC7A_CAEEL (5-302): 0: 536: 87.25		Q9N537_CAEEL (5-106): 1.15e-20: 88.8: 16.54