HitPredict

Interactor 1: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Interactor 2: SCRIB (Q7KRY7)
Protein lap4 (Protein scribble) (Protein smell-impaired)
Gene: SCRIB

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	15710747
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Metallophos~PDZ, PDZ~STPPase_N
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 302 Dm			1 1851
+	Hs
		737799 PP1G_HUMAN (3-301): 0: 549: 93.31		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		905890 PP1A_HUMAN (2-301): 0: 549: 92.67		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		906454 PP1B_HUMAN (1-302): 0: 538: 87.79		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		738009 PP1G_HUMAN (3-301): 0: 549: 93.31		LRRC1_HUMAN (1-438): 5.46e-114: 374: 59.59
+	Hs
		906110 PP1A_HUMAN (2-301): 0: 549: 92.67		LRRC1_HUMAN (1-438): 5.46e-114: 374: 59.59
+	Hs
		906581 PP1B_HUMAN (1-302): 0: 538: 87.79		LRRC1_HUMAN (1-438): 5.46e-114: 374: 59.59
+	Mm
		906292 PP1A_MOUSE (2-301): 0: 550: 92.33		LRRC1_MOUSE (1-433): 1.04e-107: 356: 60.05
+	Hs
		737994 PP1G_HUMAN (3-301): 0: 549: 93.31		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		906094 PP1A_HUMAN (2-301): 0: 549: 92.67		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Dm
		524646 PP12_DROME (1-302): 0: 547: 100.00		SUR8_DROME (1-172): 1.03e-40: 163: 27.17
+	Hs
		738129 PP1G_HUMAN (3-301): 0: 549: 93.31		SHOC2_HUMAN (1-125): 9.29e-27: 119: 28.57
+	Hs
		906202 PP1A_HUMAN (2-301): 0: 549: 92.67		SHOC2_HUMAN (1-125): 9.29e-27: 119: 28.57
+	Hs
		906638 PP1B_HUMAN (1-302): 0: 538: 87.79		SHOC2_HUMAN (1-125): 9.29e-27: 119: 28.57
+	Hs
		905921 PP1A_HUMAN (2-301): 0: 549: 92.67		DLG2_HUMAN (867-1017): 8.2e-10: 66.2: 32.68