HitPredict

Interactor 1: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Interactor 2: Q7KU01 (Q7KU01)
Phosphatase 1 nuclear targeting subunit, isoform D (Phosphatase 1 nuclear targeting subunit, isoform E)
Gene: PNUTS

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	24204300, 17007873
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 302 Dm			1 1135
+	Dm
		524617 PP12_DROME (1-302): 0: 547: 100.00		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		819210 PP11_DROME (1-301): 0: 547: 96.68		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		819214 PP11_DROME (1-301): 0: 547: 96.68		Q7KU01_DROME (1-1135): 2.29e-141: 457: 100.00
+	Dm
		984175 PP13_DROME (1-302): 0: 539: 93.71		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		984179 PP13_DROME (1-302): 0: 539: 93.71		Q7KU01_DROME (1-1135): 2.29e-141: 457: 100.00
+	Dm
		819262 PP1B_DROME (1-302): 0: 530: 85.48		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		984187 PP13_DROME (1-302): 0: 539: 93.71		Q960J4_DROME (750-1135): 1.53e-71: 245: 100.00
+	Hs
		737988 PP1G_HUMAN (3-301): 0: 549: 93.31		PP1RA_HUMAN (4-558): 7.19e-34: 143: 16.01
+	Hs
		906092 PP1A_HUMAN (2-301): 0: 549: 92.67		PP1RA_HUMAN (4-558): 7.19e-34: 143: 16.01
+	Hs
		906568 PP1B_HUMAN (1-302): 0: 538: 87.79		PP1RA_HUMAN (4-558): 7.19e-34: 143: 16.01
+	Hs
		102367 PP1B_HUMAN (1-302): 0: 538: 87.79		G3V1L9_HUMAN (115-911): 3.86e-26: 118: 9.13
+	Hs
		906425 PP1B_HUMAN (1-302): 0: 538: 87.79		ZO1_HUMAN (115-911): 3.76e-26: 118: 9.13
+	Dm
		113980 PP1B_DROME (1-302): 0: 530: 85.48		M9PB30_DROME (425-1053): 4.57e-25: 115: 10.74
+	Ce
		821920 GLC7B_CAEEL (3-301): 0: 550: 90.97		MEL28_CAEEL (175-774): 2.03e-15: 84: 10.35
+	Hs
		905838 PP1A_HUMAN (2-301): 0: 549: 92.67		ANK2_HUMAN (230-722): 1.3e-14: 81.4: 17.22
+	Hs
		270586 PP1G_HUMAN (3-301): 0: 549: 93.31		MYCB2_HUMAN (238-696): 2.94e-12: 73.7: 19.83
+	Ce
		1090117 GLC7A_CAEEL (5-302): 0: 536: 87.25		MEL28_CAEEL (175-774): 2.03e-15: 84: 10.35
+	Hs
		905894 PP1A_HUMAN (2-301): 0: 549: 92.67		MDC1_HUMAN (84-1012): 1.13e-10: 68.5: 8.29
+	Hs
		738130 PP1G_HUMAN (3-301): 0: 549: 93.31		SRRM2_HUMAN (94-951): 9.58e-10: 65.5: 8.21
+	Dm
		115296 PP1B_DROME (1-302): 0: 530: 85.48		M9PEP8_DROME (114-882): 7.45e-11: 69.1: 7.92