HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9488450
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 837
+	Hs
		523913 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		KAT2A_HUMAN (75-837): 0: 1159: 100.00
+	Hs
		523914 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		KAT2B_HUMAN (84-837): 0: 1095: 74.31
+	Hs
		170235 XRCC5_HUMAN (1-732): 0: 755: 100.00		TIF1A_HUMAN (626-832): 1.23e-44: 176: 22.86
+	Hs
		524894 XRCC5_HUMAN (1-732): 0: 755: 100.00		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		525104 XRCC5_HUMAN (1-732): 0: 755: 100.00		TRI33_HUMAN (630-836): 1.1e-36: 151: 19.74
+	Hs
		243859 XRCC5_HUMAN (1-732): 0: 755: 100.00		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		524997 XRCC5_HUMAN (1-732): 0: 755: 100.00		PHIP_HUMAN (729-831): 2.23e-15: 83.3: 21.70
+	Hs
		525080 XRCC5_HUMAN (1-732): 0: 755: 100.00		BAZ1A_HUMAN (735-834): 1e-11: 71.2: 30.00
+	Hs
		170234 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		TIF1A_HUMAN (626-832): 1.23e-44: 176: 22.86
+	Hs
		523701 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		BPTF_HUMAN (730-830): 2.17e-38: 157: 49.51
+	Hs
		523699 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		524066 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		BAZ2A_HUMAN (647-837): 1.05e-36: 151: 22.51
+	Hs
		243858 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		523873 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		TAF1L_HUMAN (727-831): 8.11e-12: 71.6: 34.26
+	Hs
		524031 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		BAZ1A_HUMAN (735-834): 1e-11: 71.2: 30.00
+	Hs
		523519 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		TAF1_HUMAN (733-831): 8.58e-09: 61.6: 30.30