HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: IGSF8 (Q969P0)
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)
Gene: IGSF8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23463506
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 613
+	Hs
		523920 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		255472 XRCC5_HUMAN (1-732): 0: 755: 100.00		OBSL1_HUMAN (92-559): 2.57e-11: 69.3: 15.13
+	Hs
		523522 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		FGFR2_HUMAN (70-300): 6.05e-20: 96.4: 12.97
+	Hs
		523903 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		255471 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		OBSL1_HUMAN (92-559): 2.57e-11: 69.3: 15.13