HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: ZBT18 (Q99592)
Zinc finger and BTB domain-containing protein 18 (58 kDa repressor protein) (Transcriptional repressor RP58) (Translin-associated zinc finger protein 1) (TAZ-1) (Zinc finger protein 238) (Zinc finger protein C2H2-171)
Gene: ZBTB18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3134
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 522
+	Mm
		650035 XRCC5_MOUSE (1-732): 0: 744: 78.31		ZBT7B_MOUSE (1-507): 7.67e-86: 277: 22.84
+	Hs
		312011 XRCC5_HUMAN (1-732): 0: 755: 100.00		ZBT7A_HUMAN (439-522): 1.75e-29: 124: 27.06
+	Hs
		161780 XRCC5_HUMAN (1-732): 0: 755: 100.00		ZN263_HUMAN (370-478): 6.18e-10: 63.9: 34.86
+	Mm
		617182 XRCC6_MOUSE (3-627): 7.65e-138: 420: 14.09		ZBT7B_MOUSE (1-507): 7.67e-86: 277: 22.84
+	Hs
		312010 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		ZBT7A_HUMAN (439-522): 1.75e-29: 124: 27.06
+	Hs
		161779 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		ZN263_HUMAN (370-478): 6.18e-10: 63.9: 34.86
+	Hs
		69707 B1AHC9_HUMAN (37-609): 1.72e-126: 389: 14.33		ZBT18_HUMAN (438-521): 3.04e-22: 101: 21.65