HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 125
+	Hs
		524861 XRCC5_HUMAN (1-732): 0: 755: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305935 XRCC5_HUMAN (1-732): 0: 755: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		523992 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		523637 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305934 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		523996 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46