HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21549307
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008094 - ATP-dependent activity, acting on DNA and 1 others more... GO:0016887 - ATP hydrolysis activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1026
+	Hs
		524897 XRCC5_HUMAN (1-732): 0: 755: 100.00		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		524888 XRCC5_HUMAN (1-732): 0: 755: 100.00		ERCC6_HUMAN (21-1021): 0: 595: 20.53
+	Hs
		229294 XRCC5_HUMAN (1-732): 0: 755: 100.00		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		524000 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		SMRCD_HUMAN (1-1026): 0: 903: 100.00
+	Hs
		523609 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		524050 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Hs
		524019 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		523703 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		229293 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		524032 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		HELLS_HUMAN (479-999): 1.2e-93: 318: 37.59