HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: PHRF1 (Q9P1Y6)
PHD and RING finger domain-containing protein 1
Gene: PHRF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25855964
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1649
+	Hs
		524047 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		PHRF1_HUMAN (1-1649): 0: 666: 100.00
+	Hs
		524829 XRCC5_HUMAN (1-732): 0: 755: 100.00		ATRX_HUMAN (141-1361): 1.06e-59: 230: 10.43
+	Hs
		525080 XRCC5_HUMAN (1-732): 0: 755: 100.00		BAZ1A_HUMAN (127-506): 1.14e-53: 209: 16.05
+	Hs
		524928 XRCC5_HUMAN (1-732): 0: 755: 100.00		CHD4_HUMAN (16-273): 6.57e-44: 178: 23.72
+	Hs
		524897 XRCC5_HUMAN (1-732): 0: 755: 100.00		CHD3_HUMAN (29-273): 4.36e-42: 172: 23.32
+	Hs
		525030 XRCC5_HUMAN (1-732): 0: 755: 100.00		UHRF1_HUMAN (140-278): 8.11e-28: 124: 28.87
+	Hs
		525022 XRCC5_HUMAN (1-732): 0: 755: 100.00		UHRF2_HUMAN (186-278): 3.66e-23: 109: 34.38
+	Hs
		523579 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		ATRX_HUMAN (141-1361): 1.06e-59: 230: 10.43
+	Hs
		524031 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		BAZ1A_HUMAN (127-506): 1.14e-53: 209: 16.05
+	Hs
		523760 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		CHD4_HUMAN (16-273): 6.57e-44: 178: 23.72
+	Hs
		523958 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		SCAFB_HUMAN (848-1646): 5.14e-44: 178: 19.58
+	Hs
		523703 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		CHD3_HUMAN (29-273): 4.36e-42: 172: 23.32
+	Hs
		523947 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		UHRF2_HUMAN (186-278): 3.66e-23: 109: 34.38