HitPredict

Interactor 1: COX41 (P13073)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1)
Gene: COX4I1

Interactor 2: COX5A (P20674)
Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)
Gene: COX5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	29568061, 34079125, 28514442, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	COX4~COX5A
Common GO terms	GO:0004129 - cytochrome-c oxidase activity GO:0005743 - mitochondrial inner membrane GO:0005751 - mitochondrial respiratory chain complex IV GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen GO:0031966 - mitochondrial membrane and 1 others more... GO:0045333 - cellular respiration
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 169 Hs			1 150
+	Hs
		594951 COX42_HUMAN (1-169): 3.8e-66: 201: 49.71		COX5A_HUMAN (1-150): 7.7e-88: 254: 100.00