Interactor 1: TOP3 (P13099)
DNA topoisomerase 3 (EC 5.6.2.1) (DNA topoisomerase III)
Gene: TOP3
Interactor 2: SGS1 (P35187)
ATP-dependent helicase SGS1 (EC 5.6.2.4) (DNA 3'-5' helicase Sgs1) (Helicase TPS1)
Gene: SGS1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12200140, 10862619, 20811460, 11523801, 7736577, 11124263, 12036100, 15899853, 27298337, 27373152, 17693398, 31351878, 19158389, 37968396, 25588990, 18272435, 32504558, 20389284 |
| Identification Methods | coimmunoprecipitation, comigration in non denaturing gel electrophoresis, anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DEAD~Toprim |
| Common GO terms | GO:0000724 - double-strand break repair via homologous recombination GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006265 - DNA topological change GO:0031422 - RecQ family helicase-topoisomerase III complex |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
