HitPredict

Interactor 1: GP1BB (P13224)
Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c)
Gene: GP1BB

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 206 Hs			1 193
+	Hs
		894276 PXDN_HUMAN (2-165): 3.11e-45: 162: 16.97		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		195857 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		195859 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		195848 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		195860 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		195856 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		195849 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		195855 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		195858 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120219 FLRT2_HUMAN (6-157): 5.24e-35: 132: 20.37		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		302717 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		302720 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		302704 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		302721 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		302716 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		302707 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		302715 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		302719 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120253 SLIK5_HUMAN (48-164): 1.12e-19: 88.2: 20.83		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		120524 SLIK4_HUMAN (55-160): 3.35e-19: 87: 27.10		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98