Interactor 1: IL7 (P13232)
Interleukin-7 (IL-7)
Gene: IL7
Interactor 2: IL7RA (P16871)
Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127)
Gene: IL7R
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.82 | 0.90 | 0.860 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 1558969, 8409434, 19141282, 8266077 |
| Identification Methods | affinity chromatography technology, surface plasmon resonance, x-ray crystallography, enzyme linked immunosorbent assay, protein cross-linking with a bifunctional reagent, cross-linking study, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL7~fn3, FN3_7~IL7 |
| Common GO terms | GO:0005576 - extracellular region GO:0008284 - positive regulation of cell population proliferation GO:0019221 - cytokine-mediated signaling pathway GO:0042100 - B cell proliferation |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
