Interactor 1: PYRE (P13298)
Orotate phosphoribosyltransferase 1 (OPRT 1) (OPRTase 1) (EC 2.4.2.10)
Gene: URA5

Interactor 2: PYRX (P30402)
Orotate phosphoribosyltransferase 2 (OPRT 2) (OPRTase 2) (EC 2.4.2.10)
Gene: URA10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 16554755, 37968396
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pribosyltran~Pribosyltran
Common GO terms GO:0004588 - orotate phosphoribosyltransferase activity
GO:0005737 - cytoplasm
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221 - pyrimidine nucleotide biosynthetic process
GO:0044205 - 'de novo' UMP biosynthetic process
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 226
Sc

1 227
+ Sc
+ Hs
+ Ce
+ Cj
+ Sp
+ At
+ Ec
+ At
+ At
+ At
+ Cj
+ At
+ Sp
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024