HitPredict

Interactor 1: FOSB (P13346)
Protein FosB (FBJ osteosarcoma oncogene B) (Transcription factor AP-1 subunit FosB)
Gene: FOSB

Interactor 2: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21258411
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 338 Mm			1 488
+	Hs
		345504 FOS_HUMAN (1-338): 3.45e-35: 133: 37.22		HDAC2_HUMAN (1-488): 0: 707: 99.39
+	Mm
		450547 JUNB_MOUSE (84-224): 1.08e-28: 115: 23.45		HDAC2_MOUSE (1-488): 0: 706: 100.00
+	Mm
		936396 ATF3_MOUSE (81-237): 5.38e-28: 109: 31.29		HDAC2_MOUSE (1-488): 0: 706: 100.00
+	Mm
		936382 JDP2_MOUSE (86-239): 3.26e-24: 98.6: 29.87		HDAC2_MOUSE (1-488): 0: 706: 100.00
+	Mm
		140216 JUNB_MOUSE (84-224): 1.08e-28: 115: 23.45		HDAC1_MOUSE (1-446): 0: 647: 89.46
+	Dm
		576068 JRA_DROME (47-230): 1.83e-26: 108: 19.79		HDAC1_DROME (5-472): 0: 654: 77.71
+	Dm
		599218 FOSLA_DROME (37-333): 6.28e-25: 107: 22.36		HDAC1_DROME (5-472): 0: 654: 77.71
+	Hs
		157201 BACH1_HUMAN (160-324): 3.89e-24: 105: 18.68		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	Mm
		140255 JDP2_MOUSE (86-239): 3.26e-24: 98.6: 29.87		HDAC1_MOUSE (1-446): 0: 647: 89.46
+	Hs
		579204 ATF3_HUMAN (81-237): 1.57e-24: 100: 29.45		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	Hs
		1038579 JDP2_HUMAN (86-239): 1.21e-24: 99.8: 29.87		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	Hs
		548245 FOSL1_HUMAN (95-338): 1.97e-23: 99.4: 37.30		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	Ce
		105173 FOS1_CAEEL (78-265): 6.03e-28: 115: 20.75		HDA1_CAEEL (7-456): 0: 596: 64.02
+	Mm
		1141349 ATF3_MOUSE (81-237): 5.38e-28: 109: 31.29		Q9JM08_MOUSE (10-431): 0: 569: 57.78
+	Sp
		223487 ATF1_SCHPO (3-243): 1.13e-26: 112: 21.31		CLR6_SCHPO (6-406): 0: 564: 60.64
+	Hs
		177189 ATF3_HUMAN (81-237): 1.57e-24: 100: 29.45		HDAC3_HUMAN (10-431): 0: 575: 58.02
+	Mm
		957049 JDP2_MOUSE (86-239): 3.26e-24: 98.6: 29.87		Q9JM08_MOUSE (10-431): 0: 569: 57.78
+	Mm
		404159 JUN_MOUSE (141-224): 3.17e-15: 77.4: 27.59		Q9JM08_MOUSE (10-431): 0: 569: 57.78
+	Hs
		579232 ATF3_HUMAN (81-237): 1.57e-24: 100: 29.45		HDAC6_HUMAN (11-363): 7.53e-102: 332: 24.04
+	Hs
		1264525 JDP2_HUMAN (86-239): 1.21e-24: 99.8: 29.87		HDAC6_HUMAN (11-363): 7.53e-102: 332: 24.04