HitPredict

Interactor 1: MYF5 (P13349)
Myogenic factor 5 (Myf-5) (Class C basic helix-loop-helix protein 2) (bHLHc2)
Gene: MYF5

Interactor 2: ID2 (Q02363)
DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2)
Gene: ID2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9242638
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0046983 - protein dimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 134
+	Hs
		526742 MYF5_HUMAN (1-255): 8.04e-88: 262: 100.00		ID1_HUMAN (14-133): 1.58e-45: 146: 45.39
+	Hs
		526744 MYF5_HUMAN (1-255): 8.04e-88: 262: 100.00		ID3_HUMAN (1-133): 8.38e-44: 141: 39.13
+	Mm
		485939 MYOD1_MOUSE (7-255): 8.65e-56: 183: 43.29		ID2_MOUSE (1-134): 1.14e-70: 209: 98.51
+	Hs
		545958 MYOD1_HUMAN (7-255): 1.76e-54: 179: 42.67		ID2_HUMAN (1-134): 1.82e-70: 209: 100.00
+	Mm
		485951 MYOD1_MOUSE (7-255): 8.65e-56: 183: 43.29		Q6GTZ3_MOUSE (15-133): 8.44e-45: 144: 46.83
+	Hs
		545945 MYOD1_HUMAN (7-255): 1.76e-54: 179: 42.67		ID1_HUMAN (14-133): 1.58e-45: 146: 45.39
+	Hs
		545959 MYOD1_HUMAN (7-255): 1.76e-54: 179: 42.67		ID3_HUMAN (1-133): 8.38e-44: 141: 39.13
+	Mm
		485938 MYOD1_MOUSE (7-255): 8.65e-56: 183: 43.29		ID3_MOUSE (1-133): 1.2e-41: 135: 38.41
+	Hs
		546071 MYOG_HUMAN (9-220): 2.93e-44: 150: 38.12		ID1_HUMAN (14-133): 1.58e-45: 146: 45.39
+	Hs
		616610 MYF6_HUMAN (9-227): 3.4e-45: 153: 38.72		ID4_HUMAN (33-109): 7.03e-31: 109: 54.12
+	Hs
		546072 MYOG_HUMAN (9-220): 2.93e-44: 150: 38.12		ID4_HUMAN (33-109): 7.03e-31: 109: 54.12
+	Mm
		589139 TAL1_MOUSE (62-241): 5.84e-31: 118: 22.10		ID1_MOUSE (15-123): 2.97e-41: 136: 50.00
+	Hs
		524547 LYL1_HUMAN (58-202): 1.84e-21: 92.3: 21.92		ID1_HUMAN (14-133): 1.58e-45: 146: 45.39
+	Hs
		524557 LYL1_HUMAN (58-202): 1.84e-21: 92.3: 21.92		ID3_HUMAN (1-133): 8.38e-44: 141: 39.13
+	Hs
		568188 TAL1_HUMAN (62-241): 1.47e-32: 123: 23.20		ID4_HUMAN (33-109): 7.03e-31: 109: 54.12
+	Hs
		814916 NGN3_HUMAN (23-208): 5.67e-29: 110: 21.16		ID4_HUMAN (33-109): 7.03e-31: 109: 54.12
+	Hs
		524549 LYL1_HUMAN (58-202): 1.84e-21: 92.3: 21.92		ID4_HUMAN (33-109): 7.03e-31: 109: 54.12