Interactor 1: DPOLA (P13382)
DNA polymerase alpha catalytic subunit A (EC 2.7.7.7) (DNA polymerase I subunit A) (DNA polymerase alpha:primase complex p180 subunit) (DNA polymerase-primase complex p180 subunit) (Pol alpha-primase complex p180 subunit)
Gene: POL1

Interactor 2: DPOE (P21951)
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase II subunit A)
Gene: POL2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 3888995, 2037567, 6376490
Identification Methods affinity chromatography technology, coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_B~DNA_pol_B, DNA_pol_B~DNA_pol_B_exo1, DNA_pol_B_exo1~DNA_pol_B_exo1, DNA_pol_B~zf-DNA_Pol
Common GO terms GO:0000166 - nucleotide binding
GO:0003697 - single-stranded DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005657 - replication fork
GO:0006272 - leading strand elongation
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1468
Sc

1 2222
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024