HitPredict

Interactor 1: TDGF1 (P13385)
Protein Cripto (Cripto, EGF-CFC family member) (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) (Teratocarcinoma-derived growth factor 1)
Gene: CRIPTO

Interactor 2: BMPR2 (Q13873)
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
Gene: BMPR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28126904
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001568 - blood vessel development GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0009952 - anterior/posterior pattern specification GO:0009986 - cell surface and 1 others more... GO:0016324 - apical plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 188 Hs			1 1038
+	Hs
		526879 TDGF1_HUMAN (1-188): 2.42e-120: 339: 100.00		BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75
+	Hs
		526889 TDGF1_HUMAN (1-188): 2.42e-120: 339: 100.00		AVR2B_HUMAN (11-513): 2.43e-125: 393: 34.37
+	Hs
		526876 TDGF1_HUMAN (1-188): 2.42e-120: 339: 100.00		AVR2A_HUMAN (11-515): 1.01e-122: 386: 32.49
+	Hs
		526881 TDGF1_HUMAN (1-188): 2.42e-120: 339: 100.00		TGFR2_HUMAN (8-521): 1.09e-118: 378: 29.66
+	Hs
		526886 TDGF1_HUMAN (1-188): 2.42e-120: 339: 100.00		ACVR1_HUMAN (53-512): 1.91e-117: 372: 29.27
+	Mm
		646091 TDGF1_MOUSE (6-182): 2.3e-99: 286: 67.23		AVR2B_MOUSE (11-513): 6.56e-123: 388: 33.15
+	Hs
		526880 TDGF1_HUMAN (1-188): 2.42e-120: 339: 100.00		ACV1B_HUMAN (59-512): 3.73e-101: 329: 29.07