Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: TF3B (P29056)
Transcription factor IIIB 70 kDa subunit (TFIIIB) (B-related factor 1) (BRF-1)
Gene: BRF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 7797524, 7568218, 24277937, 10788514, 30593915, 12052880, 8340360, 12660736, 10329159, 8662956, 8078782, 16554755, 9488485, 37968396
Identification Methods affinity chromatography technology, comigration in non denaturing gel electrophoresis, x-ray crystallography, pull down, two hybrid, coimmunoprecipitation, biochemical, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BRF1~TBP, TBP~TFIIB
Common GO terms GO:0000126 - transcription factor TFIIIB complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006352 - DNA-templated transcription initiation
GO:0006359 - regulation of transcription by RNA polymerase III
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 240
Sc

1 596
+ Hs
+ Dm
+ Sp
+ Dm
+ Sc
+ Hs
+ Mm
+ Dm
+ Dm
+ Hs
+ Hs
+ At
+ Pf

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Last updated: 15 Jul 2024