Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: T2AG (P32774)
Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA 13.5 kDa subunit) (Transcription initiation factor IIA small chain) (Transcription initiation factor IIA small subunit)
Gene: TOA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 8183347, 9447997, 8629014, 11223526, 12527429, 8754846, 8610010, 7862117, 10675336, 15132995, 15340090, 11048951, 9488485, 19098311, 23267104
Identification Methods comigration in non denaturing gel electrophoresis, affinity chromatography technology, x-ray crystallography, pull down, miniaturized immunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains TBP~TFIIA_gamma_C
Common GO terms GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005672 - transcription factor TFIIA complex
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 240
Sc

1 122
+ Dm
+ Hs
+ Dm
+ Hs

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Last updated: 15 Jul 2024