Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: TAF1 (P46677)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (TAFII-130) (TAFII-145) (TBP-associated factor 1) (TBP-associated factor 145 kDa)
Gene: TAF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 7935765, 9154807, 9447997, 12215531, 8962109, 9488488, 11805826, 23851461, 12052880, 10788514, 12524336, 10751405, 8340360, 8083216, 7667272, 9844639, 12697819, 10783167, 8662725, 16429126 and 12 others

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Identification Methods affinity chromatography technology, biochemical, coimmunoprecipitation, filter binding, molecular sieving, tandem affinity purification, x-ray crystallography, pull down, two hybrid, unspecified method and 1 others

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Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DUF3591~TBP
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005669 - transcription factor TFIID complex
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

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Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 240
Sc

1 1066
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ At

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Last updated: 15 Jul 2024