HitPredict

Interactor 1: SPTCA (P13395)
Spectrin alpha chain
Gene: alpha-Spec

Interactor 2: ACT3 (P53501)
Actin-57B (EC 3.6.4.-)
Gene: Act57B

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29249285
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0050807 - regulation of synapse organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2415 Dm			1 376
+	Dm
		501483 SPTCA_DROME (1-2415): 0: 624: 100.00		ACT1_DROME (1-376): 0: 608: 96.28
+	Dm
		501441 SPTCA_DROME (1-2415): 0: 624: 100.00		ACT5_DROME (1-376): 0: 607: 99.20
+	Dm
		361136 SPTCA_DROME (1-2415): 0: 624: 100.00		ACT2_DROME (1-376): 0: 606: 96.28
+	Dm
		527091 SPTCA_DROME (1-2415): 0: 624: 100.00		ACT6_DROME (1-376): 0: 604: 97.34
+	Dm
		361165 SPTCA_DROME (1-2415): 0: 624: 100.00		ACT4_DROME (1-376): 0: 599: 96.54
+	Hs
		891755 SPTN1_HUMAN (10-2415): 1.94e-179: 613: 63.98		ACTB_HUMAN (3-376): 0: 605: 95.46
+	Hs
		929856 SPTN1_HUMAN (10-2415): 1.94e-179: 613: 63.98		ACTG_HUMAN (3-376): 0: 604: 94.92
+	Hs
		932145 SPTN1_HUMAN (10-2415): 1.94e-179: 613: 63.98		ACTC_HUMAN (2-376): 0: 599: 92.53
+	Hs
		932975 SPTN1_HUMAN (10-2415): 1.94e-179: 613: 63.98		ACTS_HUMAN (2-376): 0: 599: 92.53
+	Hs
		164588 SPTN2_HUMAN (115-1879): 1.3e-66: 253: 18.92		ACTB_HUMAN (3-376): 0: 605: 95.46
+	Hs
		506816 SPTB1_HUMAN (5-1573): 1.71e-64: 246: 19.76		ACTB_HUMAN (3-376): 0: 605: 95.46
+	Hs
		891697 SPTB2_HUMAN (1135-2380): 1.09e-32: 142: 17.57		ACTB_HUMAN (3-376): 0: 605: 95.46
+	Hs
		929824 SPTB2_HUMAN (1135-2380): 1.09e-32: 142: 17.57		ACTG_HUMAN (3-376): 0: 604: 94.92
+	Hs
		932107 SPTB2_HUMAN (1135-2380): 1.09e-32: 142: 17.57		ACTC_HUMAN (2-376): 0: 599: 92.53
+	Hs
		892003 CP250_HUMAN (1-878): 4.53e-26: 120: 7.95		ACTB_HUMAN (3-376): 0: 605: 95.46
+	Hs
		891706 DYST_HUMAN (720-2406): 4.42e-25: 117: 8.74		ACTB_HUMAN (3-376): 0: 605: 95.46
+	Hs
		828573 CENPF_HUMAN (1371-2407): 2.25e-25: 118: 8.39		ACTC_HUMAN (2-376): 0: 599: 92.53
+	Hs
		932113 DYST_HUMAN (720-2406): 4.42e-25: 117: 8.74		ACTC_HUMAN (2-376): 0: 599: 92.53
+	Dm
		361167 ACTN_DROME (678-1113): 9.69e-19: 95.9: 14.44		ACT4_DROME (1-376): 0: 599: 96.54
+	Hs
		211548 ACTN4_HUMAN (1821-2158): 1.76e-13: 78.6: 22.87		ACTB_HUMAN (3-376): 0: 605: 95.46