Interactor 1: SPTCA (P13395)
Spectrin alpha chain
Gene: alpha-Spec

Interactor 2: Q7KV70 (Q7KV70)
Karst, isoform C (Karst, isoform H)
Gene: kst

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.933

The method score is based on:

Property Details
Experiments 11076973, 25712476, 27231092, 25381248, 29802406, 22036573
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CH~EF-hand_7, CH~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, CH~Spectrin, Spectrin~Spectrin
Common GO terms GO:0003779 - actin binding
GO:0005886 - plasma membrane
GO:0007009 - plasma membrane organization
GO:0008017 - microtubule binding
GO:0016324 - apical plasma membrane
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 2415
Dm

1 4207
+ Dm
+ Dm
+ Rn
+ Dm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024