HitPredict

Interactor 1: RB (P13405)
Retinoblastoma-associated protein (p110-RB1) (pRb) (Rb) (pp105)
Gene: Rb1

Interactor 2: CCNC (Q62447)
Cyclin-C
Gene: CCNC

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15084261
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 921 Mm			1 283
+	Hs
		414150 RB_HUMAN (1-921): 0: 1290: 89.87		CCNB1_HUMAN (1-277): 4.92e-82: 255: 14.89
+	Hs
		414240 RB_HUMAN (1-921): 0: 1290: 89.87		CCNA1_HUMAN (2-262): 1.61e-78: 247: 17.74
+	Hs
		414170 RB_HUMAN (1-921): 0: 1290: 89.87		CCNC_HUMAN (1-283): 1.34e-79: 244: 99.29
+	Hs
		414164 RB_HUMAN (1-921): 0: 1290: 89.87		CCNA2_HUMAN (2-263): 3.88e-75: 237: 15.36
+	Hs
		237378 RB_HUMAN (1-921): 0: 1290: 89.87		CCNT2_HUMAN (1-278): 2.44e-69: 229: 21.99
+	Hs
		414187 RB_HUMAN (1-921): 0: 1290: 89.87		CCND2_HUMAN (10-275): 1.4e-53: 177: 16.54
+	Hs
		660112 RBL1_HUMAN (587-868): 4.17e-83: 291: 28.27		CCNA1_HUMAN (2-262): 1.61e-78: 247: 17.74
+	Hs
		590128 RBL1_HUMAN (587-868): 4.17e-83: 291: 28.27		CCNA2_HUMAN (2-263): 3.88e-75: 237: 15.36
+	Hs
		538529 RBL2_HUMAN (601-865): 4.48e-54: 206: 24.38		CCNB1_HUMAN (1-277): 4.92e-82: 255: 14.89
+	Hs
		943777 RBL2_HUMAN (601-865): 4.48e-54: 206: 24.38		CCNA1_HUMAN (2-262): 1.61e-78: 247: 17.74
+	Hs
		590169 RBL2_HUMAN (601-865): 4.48e-54: 206: 24.38		CCNA2_HUMAN (2-263): 3.88e-75: 237: 15.36
+	Hs
		673066 RBL2_HUMAN (601-865): 4.48e-54: 206: 24.38		CCND2_HUMAN (10-275): 1.4e-53: 177: 16.54