HitPredict

Interactor 1: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005802 - trans-Golgi network GO:0005886 - plasma membrane GO:0016020 - membrane GO:0043231 - intracellular membrane-bounded organelle GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 410 Hs			1 116
+	Hs
		527361 LAMP2_HUMAN (1-410): 0: 557: 100.00		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261632 LAMP2_HUMAN (1-410): 0: 557: 100.00		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		263154 LAMP2_HUMAN (1-410): 0: 557: 100.00		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180803 LAMP2_HUMAN (1-410): 0: 557: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		527468 LAMP2_HUMAN (1-410): 0: 557: 100.00		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		527764 LAMP2_HUMAN (1-410): 0: 557: 100.00		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		506936 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261630 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		506961 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263149 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180798 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		507033 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		507213 LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		850608 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261741 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		926268 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263393 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180957 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		1079470 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		1313467 LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50