HitPredict

Interactor 1: CCL2 (P13500)
C-C motif chemokine 2 (HC11) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte secretory protein JE) (Small-inducible cytokine A2)
Gene: CCL2

Interactor 2: CCL13 (Q99616)
C-C motif chemokine 13 (CK-beta-10) (Monocyte chemoattractant protein 4) (Monocyte chemotactic protein 4) (MCP-4) (NCC-1) (Small-inducible cytokine A13) [Cleaved into: C-C motif chemokine 13, long chain; C-C motif chemokine 13, medium chain; C-C motif chemokine 13, short chain]
Gene: CCL13

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 28381538, 16803905
Identification Methods pull down, mass spectrometry studies of complexes
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0002548 - monocyte chemotaxis
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006935 - chemotaxis
and 15 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 99
Hs

1 98
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Last updated: 15 Jul 2024