HitPredict

Interactor 1: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Interactor 2: CCR4 (P51679)
C-C chemokine receptor type 4 (C-C CKR-4) (CC-CKR-4) (CCR-4) (CCR4) (K5-5) (CD antigen CD194)
Gene: CCR4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	8573157
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006935 - chemotaxis GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 91 Hs			1 360
+	Hs
		486238 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR4_HUMAN (1-360): 2.26e-90: 277: 100.00
+	Hs
		134354 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		ACKR2_HUMAN (4-324): 1.53e-88: 273: 41.30
+	Hs
		134356 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		ACKR2_HUMAN (4-324): 1.53e-88: 273: 41.30
+	Hs
		134400 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		ACKR2_HUMAN (4-324): 1.53e-88: 273: 41.30
+	Hs
		486230 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR1_HUMAN (27-360): 1.43e-79: 249: 49.11
+	Hs
		561728 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR1_HUMAN (27-360): 1.43e-79: 249: 49.11
+	Hs
		526560 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR1_HUMAN (27-360): 1.43e-79: 249: 49.11
+	Hs
		783833 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR2_HUMAN (10-334): 7.48e-77: 242: 47.24
+	Hs
		486239 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR5_HUMAN (25-360): 1.7e-71: 228: 49.70
+	Hs
		561733 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR5_HUMAN (25-360): 1.7e-71: 228: 49.70
+	Hs
		486237 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR3_HUMAN (14-357): 1.14e-70: 226: 45.38
+	Hs
		561732 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR3_HUMAN (14-357): 1.14e-70: 226: 45.38
+	Hs
		526565 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR5_HUMAN (25-360): 1.7e-71: 228: 49.70
+	Hs
		849654 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR5_HUMAN (25-360): 1.7e-71: 228: 49.70
+	Hs
		526564 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR3_HUMAN (14-357): 1.14e-70: 226: 45.38
+	Hs
		849619 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR3_HUMAN (14-357): 1.14e-70: 226: 45.38
+	Hs
		1305163 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		ACKR4_HUMAN (1-350): 3.3e-70: 225: 32.67
+	Hs
		830629 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CXCR3_HUMAN (28-319): 1.12e-49: 172: 38.31
+	Hs
		486231 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CXCR5_HUMAN (16-330): 6e-47: 165: 34.26
+	Hs
		526561 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CXCR5_HUMAN (16-330): 6e-47: 165: 34.26