HitPredict

Interactor 1: IL1R1 (P13504)
Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
Gene: IL1R1

Interactor 2: MYD88 (P22366)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 17507369, 16477040, 10854325
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006954 - inflammatory response
GO:0009986 - cell surface
GO:0019221 - cytokine-mediated signaling pathway
GO:0032991 - protein-containing complex
GO:0050727 - regulation of inflammatory response
and 1 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 576
Mm

1 296
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024