Interactor 1: IL1R1 (P13504)
Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
Gene: IL1R1

Interactor 2: IL1AP (Q61730)
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (EC 3.2.2.6) (Interleukin-33 receptot beta chain)
Gene: Il1rap

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 17507369, 17675517
Identification Methods affinity chromatography technology, enzyme linked immunosorbent assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~Ig_2, Ig_3~I-set, I-set~Ig_6, Ig_2~Ig_2, Ig_2~Ig_3, Ig_2~Ig_6, TIR~TIR
Common GO terms GO:0003953 - NAD+ nucleosidase activity
GO:0004908 - interleukin-1 receptor activity
GO:0006954 - inflammatory response
GO:0019221 - cytokine-mediated signaling pathway
GO:0032991 - protein-containing complex
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 576
Mm

1 570
+ Hs
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Last updated: 15 Jul 2024