HitPredict

Interactor 1: MYH8 (P13535)
Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal)
Gene: MYH8

Interactor 2: HSPB8 (Q9UJY1)
Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (E2-induced gene 1 protein) (Heat shock protein family B member 8) (Protein kinase H11) (Small stress protein-like protein HSP22)
Gene: HSPB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1937 Hs			1 196
+	Hs
		61510 A5YM51_HUMAN (6-1929): 0: 1176: 80.87		HSPB2_HUMAN (1-170): 5.01e-42: 141: 25.88
+	Hs
		1356177 MYH2_HUMAN (721-1783): 9e-57: 220: 14.75		HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00
+	Hs
		528397 MYH6_HUMAN (726-1799): 9.86e-57: 220: 17.81		HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00
+	Hs
		1356186 MYH4_HUMAN (736-1783): 7.1e-55: 214: 15.89		HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00
+	Hs
		522580 MYH1_HUMAN (736-1706): 1.94e-54: 212: 14.89		HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00
+	Hs
		502931 MYH3_HUMAN (1209-1937): 1.71e-43: 177: 14.73		HSPB8_HUMAN (1-196): 7.92e-71: 214: 100.00
+	Hs
		528375 MYH6_HUMAN (726-1799): 9.86e-57: 220: 17.81		HSPB2_HUMAN (1-170): 5.01e-42: 141: 25.88
+	Dm
		404257 MYSA_DROME (1054-1937): 4.13e-48: 192: 15.77		Q9VSA9_DROME (37-193): 1.51e-35: 124: 24.68
+	Dm
		113819 MYSA_DROME (1054-1937): 4.13e-48: 192: 15.77		M9NHC5_DROME (67-172): 1.81e-32: 115: 27.36