HitPredict

Interactor 1: MYH8 (P13535)
Myosin-8 (Myosin heavy chain 8) (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal)
Gene: MYH8

Interactor 2: AURKC (Q9UQB9)
Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)
Gene: AURKC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1937 Hs			1 309
+	Hs
		522653 MYH7_HUMAN (6-1929): 0: 1175: 80.93		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		725220 MYH10_HUMAN (928-1937): 8.96e-63: 240: 19.90		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		568568 MYH10_HUMAN (928-1937): 8.96e-63: 240: 19.90		KAPCA_HUMAN (6-308): 1.57e-133: 384: 29.75
+	Hs
		728503 MYH11_HUMAN (956-1937): 3.89e-61: 234: 19.36		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		728527 MYH11_HUMAN (956-1937): 3.89e-61: 234: 19.36		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		1189785 MYH14_HUMAN (892-1937): 5e-57: 221: 17.56		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		528359 MYH6_HUMAN (726-1799): 9.86e-57: 220: 17.81		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		610795 MYH2_HUMAN (721-1783): 9e-57: 220: 14.75		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		1357872 MYH4_HUMAN (736-1783): 7.1e-55: 214: 15.89		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		610802 MYH4_HUMAN (736-1783): 7.1e-55: 214: 15.89		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		522582 MYH1_HUMAN (736-1706): 1.94e-54: 212: 14.89		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		522538 MYH1_HUMAN (736-1706): 1.94e-54: 212: 14.89		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		681696 MYH9_HUMAN (1088-1933): 3.19e-47: 189: 14.51		AKT1_HUMAN (5-309): 8.7e-134: 389: 29.47
+	Hs
		724962 MYH9_HUMAN (1088-1933): 3.19e-47: 189: 14.51		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		568567 MYH9_HUMAN (1088-1933): 3.19e-47: 189: 14.51		KAPCA_HUMAN (6-308): 1.57e-133: 384: 29.75
+	At
		98846 MYO17_ARATH (1181-1349): 9.29e-09: 63.2: 15.98		KIN10_ARATH (42-303): 1.11e-137: 400: 37.45