Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.916

The method score is based on:

Property Details
Experiments 26618866, 11051556, 31324722, 17110338, 29924966
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_membrane~CFTR_R, ABC_tran~ABC_tran, ABC_tran~CFTR_R
Common GO terms GO:0005254 - chloride channel activity
GO:0005260 - intracellularly ATP-gated chloride channel activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 50 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1480
Hs

1 1480
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+ Rn
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Last updated: 15 Jul 2024