Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: CD59 (P13987)
CD59 glycoprotein (1F5 antigen) (20 kDa homologous restriction factor) (HRF-20) (HRF20) (MAC-inhibitory protein) (MAC-IP) (MEM43 antigen) (Membrane attack complex inhibition factor) (MACIF) (Membrane inhibitor of reactive lysis) (MIRL) (Protectin) (CD antigen CD59)
Gene: CD59

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 0.55 0.616

The method score is based on:

Property Details
Experiments 17110338, 29924966, 31324722
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0016020 - membrane
Homologous interactions 0

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Last updated: 15 Jul 2024