HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: ML12A (P19105)
Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)
Gene: MYL12A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26618866, 31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 171
+	Hs
		159533 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37
+	Hs
		528571 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYL9_HUMAN (14-171): 2.29e-64: 196: 94.30
+	Hs
		528591 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CALL3_HUMAN (31-92): 1.25e-10: 58.2: 27.27
+	Hs
		484052 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CALM3_HUMAN (16-92): 3.58e-09: 54.5: 24.69