Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 26618866, 19398555, 21455491
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0010008 - endosome membrane
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1480
Hs

1 215
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024