HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PSA3 (P25788)
Proteasome subunit alpha type-3 (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8)
Gene: PSMA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26618866, 31324722, 16390870
Identification Methods	affinity chromatography technology, biochemical, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 255
+	Hs
		528598 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA5_HUMAN (1-239): 4.52e-96: 283: 31.97
+	Hs
		528866 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA6_HUMAN (4-242): 1.96e-95: 281: 29.34
+	Hs
		528582 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA4_HUMAN (4-236): 5.31e-94: 278: 27.43
+	Hs
		156210 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA7_HUMAN (7-237): 4.58e-93: 275: 31.76
+	Zm
		74636 K7W6A4_MAIZE (8-648): 1.11e-59: 228: 15.10		B4FDY6_MAIZE (4-248): 3.97e-98: 288: 32.00