HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PSB4 (P28070)
Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3)
Gene: PSMB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26618866, 17110338
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 264
+	Hs
		528598 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA5_HUMAN (26-252): 6.98e-77: 234: 13.69
+	Hs
		156210 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA7_HUMAN (33-255): 6.14e-76: 232: 14.16
+	Hs
		528597 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB8_HUMAN (14-254): 2.23e-75: 232: 23.29
+	Hs
		528580 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA2_HUMAN (28-258): 1.95e-74: 228: 14.23
+	Hs
		528866 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA6_HUMAN (26-261): 3.03e-74: 228: 11.69
+	Hs
		528601 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB5_HUMAN (11-252): 1.96e-70: 218: 21.07
+	Hs
		528532 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB1_HUMAN (26-246): 7.33e-70: 217: 22.61