HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)
Gene: PSMB5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26618866
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 263
+	Hs
		528597 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB8_HUMAN (1-261): 7.16e-89: 266: 57.46
+	Hs
		528598 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA5_HUMAN (28-258): 1.29e-86: 259: 15.64
+	Hs
		528580 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA2_HUMAN (30-259): 6.04e-80: 242: 18.64
+	Hs
		528582 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSA4_HUMAN (32-255): 1.03e-79: 242: 18.22
+	Hs
		528600 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PSB6_HUMAN (43-245): 4.34e-77: 235: 31.37
+	Zm
		74636 K7W6A4_MAIZE (8-648): 1.11e-59: 228: 15.10		B4FDY6_MAIZE (32-263): 7.01e-83: 250: 19.18