HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PRDX6 (P30041)
Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (24 kDa protein) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Glutathione-dependent peroxiredoxin) (Liver 2D page spot 40) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx) (Red blood cells page spot 12)
Gene: PRDX6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	26618866, 31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 224
+	Hs
		528644 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX2_HUMAN (2-204): 9.19e-90: 264: 28.99
+	Hs
		529023 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX1_HUMAN (2-204): 1.79e-87: 258: 28.37
+	Hs
		528616 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX3_HUMAN (6-204): 4.06e-86: 257: 25.12
+	Hs
		529062 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX4_HUMAN (3-204): 2.98e-83: 250: 24.76