HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: TIA1 (P31483)
Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1 isoform p40) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1)
Gene: TIA1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14966131
Identification Methods	nucleic acid uv cross-linking assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 386
+	Hs
		529208 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAP1L_HUMAN (7-241): 1.97e-48: 174: 22.59
+	Hs
		529541 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP5_HUMAN (2-187): 2.52e-44: 159: 22.63
+	Hs
		516343 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP1_HUMAN (96-297): 6.74e-33: 131: 26.70
+	Hs
		529709 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP3_HUMAN (96-297): 5.07e-30: 123: 25.73
+	Hs
		529069 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP4_HUMAN (1-98): 1.32e-20: 95.5: 21.43
+	Sc
		376791 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		PABP_YEAST (1-104): 6.86e-19: 90.1: 19.05