HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: RADI (P35241)
Radixin
Gene: RDX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26618866, 31324722
Identification Methods	affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016324 - apical plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 583
+	Hs
		528479 CFTR_HUMAN (1-1480): 0: 1031: 100.00		EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28
+	Hs
		528584 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MOES_HUMAN (1-583): 2.8e-161: 474: 80.96
+	Hs
		719757 MRP2_HUMAN (798-1466): 4.31e-56: 217: 15.74		RADI_HUMAN (1-583): 3.49e-166: 487: 100.00
+	Dm
		1098328 Q9VLN6_DROME (917-1477): 1.23e-61: 234: 17.69		MERH_DROME (3-583): 1.81e-130: 397: 40.26
+	Dm
		1098321 Q9VJ21_DROME (835-1477): 3.83e-60: 229: 16.67		MERH_DROME (3-583): 1.81e-130: 397: 40.26
+	Dm
		1098306 Q9VDT3_DROME (787-1468): 5.15e-57: 219: 14.82		MERH_DROME (3-583): 1.81e-130: 397: 40.26
+	Dm
		1098271 Q8T9B4_DROME (1169-1477): 5.97e-49: 192: 20.77		MERH_DROME (3-583): 1.81e-130: 397: 40.26