HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	26618866, 31324722, 17110338, 29924966
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 679
+	Hs
		503344 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HSP7C_HUMAN (51-653): 0: 883: 50.16
+	Hs
		528659 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HS71L_HUMAN (49-673): 0: 883: 47.59
+	Hs
		528491 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HSP76_HUMAN (49-673): 0: 875: 48.68
+	Hs
		483745 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HS71A_HUMAN (51-652): 0: 873: 49.27
+	Hs
		528829 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HSP72_HUMAN (50-653): 0: 868: 49.11
+	Hs
		501618 CFTR_HUMAN (1-1480): 0: 1031: 100.00		BIP_HUMAN (53-677): 0: 566: 50.55