HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: SPB10 (P48595)
Serpin B10 (Bomapin) (Peptidase inhibitor 10) (PI-10)
Gene: SERPINB10

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35156780
Identification Methods	protein complementation assay, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 397
+	Hs
		528609 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SPB3_HUMAN (1-397): 3.17e-160: 457: 44.72
+	Hs
		529588 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SPB12_HUMAN (1-397): 5.62e-153: 439: 41.73
+	Hs
		344101 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ANT3_HUMAN (4-397): 2.89e-144: 419: 33.33
+	Hs
		344270 CFTR_HUMAN (1-1480): 0: 1031: 100.00		AACT_HUMAN (4-397): 8.2e-145: 419: 31.23
+	Hs
		344156 CFTR_HUMAN (1-1480): 0: 1031: 100.00		A1AT_HUMAN (2-397): 5.39e-141: 409: 30.56
+	Hs
		397088 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAI1_HUMAN (4-397): 1.85e-132: 387: 26.88
+	Hs
		179386 MRP5_HUMAN (774-1479): 5.77e-53: 207: 13.26		AACT_HUMAN (4-397): 8.2e-145: 419: 31.23
+	Hs
		839495 ABCA9_HUMAN (75-736): 2.05e-40: 166: 9.96		SPB8_HUMAN (1-397): 1.19e-158: 452: 43.83