HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	31324722, 17110338, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 545
+	Hs
		529628 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		528759 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		528502 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		528794 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Sc
		760727 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		TCPG_YEAST (3-530): 0: 575: 58.88